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Results: Significant reduction in modified MASI was observed in patients treated with topical and oral glutathione ( p =0.011) and ( p =0.007) respectively, while patients treated with topical or oral placebo had no response

Drug metabolism proceeds in two phases Phase I is the addition of the polar group: the polarity of the drug is increased by oxidation or hydroxylation catalyzed by a family of microsomal cytochrome P-450 oxidases

40 Despite NBDHEXs promising anticancer activity, consideration should be given to the relatively low GST-target selectivity and poor water-solubility

It is unclear whether PDTC analog-driven proteasome inhibitors have similar protein substrate targets for tumor suppression (Yu et al., 2007

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3e, Supplementary Table 4)